FITC标记的磷酸化非受体型蛋白酪氨酸磷酸酶7抗体
产品名称： FITC标记的磷酸化非受体型蛋白酪氨酸磷酸酶7抗体
英文名称： Anti-phospho-PTPN7 (Ser93)/FITC
产品编号： HZ-5558R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-phospho-PTPN7 (Ser93)/FITC Conjugated antibody
FITC标记的磷酸化非受体型蛋白酪氨酸磷酸酶7抗体
| 英文名称 | Anti-phospho-PTPN7 (Ser93)/FITC |
| 中文名称 | FITC标记的磷酸化非受体型蛋白酪氨酸磷酸酶7抗体 |
| 别 名 | PTPN7(phospho S93); BPTP 4; BPTP4; Dual specificity phosphatase 1; Hematopoietic protein tyrosine phosphatase; LC PTP; LCPTP; LPTP; Protein tyrosine phoshatase non receptor type stress induced; Protein tyrosine phoshatase nonreceptor type stress induced; Protein tyrosine phosphatase LC PTP; Protein tyrosine phosphatase non receptor type 7; PTPN 7; PTPNI; Tyrosine protein phosphatase non receptor type 7; PTN7_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 免疫学 信号转导 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human PTPN7 around the phosphorylation site of Ser93 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]. Function: Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction. Subunit: Monomer. Interacts with MAPK1, MAPK3 and several other MAP kinases. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed exclusively in thymus and spleen. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 5778 Human Entrez Gene: 320139 Mouse Entrez Gene: 246781 Rat Omim: 176889 Human SwissProt: P35236 Human SwissProt: Q8BUM3 Mouse SwissProt: P49445 Rat Unigene: 402773 Human Unigene: 258388 Mouse Unigene: 10160 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是蛋白酪氨酸磷酸酶（PTP）家族的成员。PTPs已知是调节多种细胞过程的信号分子，包括细胞生长、分化、有丝分裂周期和致癌转化。该基因优先在多种造血细胞中表达，是淋巴因子刺激细胞中的早期应答基因。该PTP的非催化N-末端可以与MAP激酶相互作用，并抑制MAP激酶活性。该PTP被证明参与调节T细胞抗原受体（TCR）信号，这被认为是通过去磷酸化与MAP激酶通路相关的分子发挥作用。该基因已发现多个交替剪接转录变体。[由RefSeq提供]。