DMT1,金属离子转运体1抗体

产品编号HZ-3577R
英文名称DMT1
中文名称金属离子转运体1抗体
别 名DCT 1; DCT1; Divalent metal transporter 1; DMT 1; DMT1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2.
说 明 书0.1ml 0.2ml
研究领域肿瘤 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow,
DMT1,金属离子转运体1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量62kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DMT1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DMT1,金属离子转运体1抗体PubMedPubMed
产品介绍background:
DMT1 is a major transporter of ferrous iron from the intestinal lumen. DMT1 belongs to the family of NRAMP metal ion transporters which function in diverse organisms from bacteria to human. DMT1 (NRAMP2) transports metal ions at the plasma membrane of cells of both the duodenum and in peripheral tissues, and defective DMT1 causes anaemia.

Function:
Actin-bundling protein. May function in mitogen-activated protein kinase pathway.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Heart, brain, lung, skeletal muscle, and kidney.

Post-translational modifications:
Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.

Similarity:
Belongs to the villin/gelsolin family.
Contains 1 HP (headpiece) domain.

Gene ID:
4891

Database links:
Entrez Gene: 4891 Human
Entrez Gene: 18174 Mouse
Omim: 600523 Human
SwissProt: P49281 Human
SwissProt: P49282 Mouse
Unigene: 505545 Human
Unigene: 234608 Mouse

DMT1,金属离子转运体1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.