AP2S1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
AP2S1抗体

AP2S1抗体

商家询价

产品名称： AP2S1抗体

英文名称： AP2S1Antibody

产品编号： XY15634-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 AP2S1抗体

Applications
In-house applications ELISA     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
 
Recommended dilution  
 AP2S1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen AP2S1 fusion protein ag8095 Full name Adaptor-related protein complex 2, sigma 1 subunit
Calculated molecular
weight		 142aa,17 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC006337 Gene ID (NCBI) 1175
Gene symbol AP2S1 Synonyms AP 2 complex subunit sigma, AP17, AP17 DELTA, AP2S1, CLAPS2, HA2 17 kDa subunit, Sigma2 adaptin
Background AP2S1抗体

AP2S1 is a component of the adaptor protein complex 2 (AP-2). AP complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP complexes are involved in the formation of clathrin-coated vesicles (CCVs) by recruiting the scaffold protein, clathrin. AP complexes also play a pivotal role in the cargo selection by recognizing the sorting signals within the cytoplasmic tail of integral membrane proteins. AP-2 is composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1). It works on the plasma membrane to internalize cargo in clathrin-mediated endocytosis. AP2S1抗体

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