AXL monoclonal antibody, clone 7E10
产品名称: AXL monoclonal antibody, clone 7E10
英文名称: AXL monoclonal antibody, clone 7E10
产品编号: MAB10498
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant AXL.
- Immunogen:
- Recombinant hIgGFc tag fusion protein corresponding to extracellular fragment of human AXL.
- Host:
- Mouse
- Theoretical MW (kDa):
- 97.4
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Recombinant protein)
- Western blot analysis using AXL monoclonal antibody, clone 7E10 (Cat # MAB10498) against extracellular domain of human AXL (aa 19-444).
- Entrez GeneID:
- 558
- Gene Name:
- AXL
- Gene Alias:
- JTK11,UFO
- Gene Description:
- AXL receptor tyrosine kinase
- Omim ID:
- 109135
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- AXL transforming sequence/gene,oncogene AXL