Anti-MGST1抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-MGST1抗体

Anti-MGST1抗体

商家询价

产品名称: Anti-MGST1抗体

英文名称: MGST1

产品编号: YB--12206R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-MGST1抗体

产品编号 YB-12206R
英文名称 MGST1
中文名称 微粒体谷胱甘肽S转移酶1抗体
别    名 MGST1; Glutathione S transferase 12; Microsomal glutathione transferase 1; GST12; MGST 1; MGST; MGST1; MGST1_HUMAN; Microsomal glutathione S-transferase 1; Microsomal GST 1; Microsomal GST-1; Microsomal GST-I.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  发育生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MGST1:81-155/155 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]

Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.

Subcellular Location:
Microsome. Mitochondrion outer membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in liver.

Post-translational modifications:
Peroxynitrite induces nitration at Tyr-93 which activates the enzyme.

Similarity:
Belongs to the MAPEG family.

SWISS:
P10620

Gene ID:
4257

Database links:

Entrez Gene: 4257 Human

Entrez Gene: 56615 Mouse

Entrez Gene: 171341 Rat

Omim: 138330 Human

SwissProt: P10620 Human

SwissProt: Q91VS7 Mouse

SwissProt: P08011 Rat

Unigene: 389700 Human

Unigene: 14796 Mouse

Unigene: 2580 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications