BUB1 polyclonal antibody
产品名称： BUB1 polyclonal antibody
英文名称： BUB1 polyclonal antibody
产品编号： PAB13270
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BUB1.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 19 amino acids of human BUB1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A dual role for Bub1 in the spindle checkpoint and chromosome congression.
Meraldi P, Sorger PK.EMBO J. 2005 Apr 20;24(8):1621-33. Epub 2005 Mar 31.
- 2.
- Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.
Tang Z, Shu H, Oncel D, Chen S, Yu H.Mol Cell. 2004 Nov 5;16(3):387-97.
- 3.
- Mammalian BUB1 protein kinases: map positions and in vivo expression.
Pangilinan F, Li Q, Weaver T, Lewis BC, Dang CV, Spencer F.Genomics. 1997 Dec 15;46(3):379-88.
- Entrez GeneID:
- 699
- Protein Accession#:
- O43683
- Gene Name:
- BUB1
- Gene Alias:
- BUB1A,BUB1L,hBUB1
- Gene Description:
- budding uninhibited by benzimidazoles 1 homolog (yeast)
- Omim ID:
- 602452
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer. [provided by RefSeq
- Other Designations:
- BUB1 budding uninhibited by benzimidazoles 1 homolog,budding uninhibited by benzimidazoles 1,mitotic spindle checkpoint kinase,putative serine/threonine-protein kinase
- Interactome
- Gene Pathway