Anti-IL-2抗体
产品名称： Anti-IL-2抗体
英文名称： IL-2
产品编号： YB--0389M
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
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Anti-IL-2抗体
| 产品编号 | YB-0389M |
| 英文名称 | IL-2 |
| 中文名称 | 白细胞介素-2单克隆抗体 |
| 别 名 | Interleukin-2; T-cell growth factor; Aldesleukin; IL 2; Interleukin 2; Interleukin2; Lymphokine; POIL2; T Cell Growth Factor; TCGF. |
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Specific References (1) | bsm-0389M has been referenced in 1 publications.
[IF=3.17] Zhang, Jia‐xiang, et al. "Complement C5a–C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice." Journal of Applied Toxicology (2015). IHC-P ; Mouse.
PubMed:26095957
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| 规格价格 | 50ul/860元 购买 100ul/1580元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul |
| 研究领域 | 免疫学 糖蛋白 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | H2E4 |
| 交叉反应 | Human, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Recombinant human IL-2:21-153/153 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein G |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008] Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Subcellular Location: Secreted. DISEASE: Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Similarity: Belongs to the IL-2 family. SWISS: P60568 Gene ID: 3558 Database links:
Entrez Gene: 3558 Human Entrez Gene: 16183 Mouse Entrez Gene: 116562 Rat Omim: 147680 Human SwissProt: P60568 Human SwissProt: P04351 Mouse SwissProt: P17108 Rat Unigene: 89679 Human Unigene: 14190 Mouse Unigene: 9871 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-2作为一种T细胞生长因子在免疫应答及其调节中起重要作用,IL-2的拮抗剂可用于同种移植排斥、T细胞性白血病以及某些自身免疫性疾病的治疗.胞内IL-2的水平是反映Th1 /Th2型细胞平衡状态的一个有用指标,血清IL-2的水平异常增高与某些疾病密切相关 |