KIR2DL1 (Human) Recombinant Protein
产品名称： KIR2DL1 (Human) Recombinant Protein
英文名称： KIR2DL1 (Human) Recombinant Protein
产品编号： H00003802-G01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human KIR2DL1 full-length ORF (AAH69344.1) recombinant protein without tag.
- Sequence:
- MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTERMFHHVGQACLKLPTSSDPTVSACQSNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
- Theoretical MW (kDa):
- 41.4
- Form:
- Liquid
- Preparation Method:
- in vitro wheat germ expression system with proprietary liposome technology
- Storage Buffer:
- 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Note:
- Best use within three months from the date of receipt of this protein.
- Publication Reference
- 1.
- Production and partial purification of membrane proteins using a liposome-supplemented wheat cell-free translation system.
Nozawa A, Ogasawara T, Matsunaga S, Iwasaki T, Sawasaki T, Endo Y. BMC Biotechnol. 2011 Apr 11;11:35.
- Application Image
- Antibody Production
- Functional Study
- Compound Screening
- Entrez GeneID:
- 3802
- GeneBank Accession#:
- BC069344.1
- Protein Accession#:
- AAH69344.1
- Gene Name:
- KIR2DL1
- Gene Alias:
- CD158A,KIR-K64,KIR221,NKAT,NKAT1,p58.1
- Gene Description:
- killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
- Omim ID:
- 604936
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq
- Other Designations:
- killer inhibitory receptor 2-2-1,natural killer-associated transcript 1,p58 NK cell inhibitory receptor NKR-K6,p58 killer cell inhibitory receptor KIR-K64,p58 natural killer cell receptor
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Acute Disease
- Angina Pectoris
- Arthritis, Psoriatic
- Autoimmune Diseases
- Behcet Syndrome
- Carcinoma, Hepatocellular
- Celiac Disease
- Cervical Intraepithelial Neoplasia
- Cytomegalovirus Infections
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Familial Mediterranean Fever
- Familial Mediterranean fever
- Gastritis
- Genetic Predisposition to Disease
- Graft vs Host Disease