FITC标记的接触蛋白相关蛋白3抗体
产品名称： FITC标记的接触蛋白相关蛋白3抗体
英文名称： Anti-CNTNAP3 /FITC
产品编号： HZ-11075R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CNTNAP3 /FITC Conjugated antibody
FITC标记的接触蛋白相关蛋白3抗体
| 产品编号 | bs-11075R-FITC |
| 英文名称 | Anti-CNTNAP3 /FITC |
| 中文名称 | FITC标记的接触蛋白相关蛋白3抗体 |
| 别 名 | CASPR3; Cell recognition molecule Caspr3; CNTNAP3A; Contactin associated protein like 3; contactin associated protein-like 3B; FLJ14195; KIAA1714; CNTP3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 细胞粘附分子 跨膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 138kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CNTNAP3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: CNTNAP3B is a 1,288 amino acid protein that is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias. Function: The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined. Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 2: Secreted Similarity: Belongs to the neurexin family. Contains 2 EGF-like domains. Contains 1 F5/8 type C domain. Contains 1 fibrinogen C-terminal domain. Contains 4 laminin G-like domains. Database links: UniProtKB/Swiss-Prot: Q9BZ76.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CNTNAP3B是一种由1288个氨基酸编码的蛋白质，该基因被映射到人类9号染色体。第9号染色体含有1亿4500万个碱基对，包含4%个人类基因组，编码近900个基因。遗传性出血性毛细血管扩张症，其特征是有害的血管缺陷和家族性精神障碍，都与9号染色体有关。值得注意的是，9号染色体包含最大的干扰素家族基因簇。染色体9与易位的22号染色体相关联，导致BCR-ABL融合蛋白在白血病中的异常生成。