Cadherin 26,钙粘蛋白26抗体

产品编号HZ-13718R
英文名称Cadherin 26
中文名称钙粘蛋白26抗体
别 名Cadherin-26; CAD26_HUMAN; Cadherin 26; Cadherin like 26; Cadherin-like protein 26; Cadherin-like protein VR20; Cdh26; RP4-551D2.3; VR20.
说 明 书0.1ml 0.2ml
研究领域细胞生物 通道蛋白 细胞粘附分子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
Cadherin 26,钙粘蛋白26抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量92kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Cadherin 26
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cadherin 26,钙粘蛋白26抗体PubMedPubMed
产品介绍background:
Cadherins comprise a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. Cadherin-26 is a 852 amino acid single-pass transmembrane protein containing 4 cadherin domains through which it interacts with other cadherins in a homophilic manner. There are 4 named isoforms of cadherin-26 that are produced as a result of alternative spicing events.

Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular Location:
Cell membrane.

Similarity:
Contains 4 cadherin domains.

Gene ID:
60437

Database links:
Entrez Gene: 60437 Human
SwissProt: Q8IXH8 Human
Unigene: 729046 Human

Cadherin 26,钙粘蛋白26抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.