FITC标记的肿瘤/睾丸抗原44抗体
产品名称： FITC标记的肿瘤/睾丸抗原44抗体
英文名称： Anti-TPTE/FITC
产品编号： HZ-7955R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-TPTE/FITC Conjugated antibody
FITC标记的肿瘤/睾丸抗原44抗体
| 英文名称 | Anti-TPTE/FITC |
| 中文名称 | FITC标记的肿瘤/睾丸抗原44抗体 |
| 别 名 | Cancer/testis antigen 44; CT44; EC=3.1.3.48; HGNC:12023; PTEN2; Putative tyrosine protein phosphatase; Putative tyrosine-protein phosphatase TPTE; TPTE; TPTE_HUMAN; Transmembrane phosphatase with tensin homology; Tumor antigen BJ HCC 5; Tumor antigen BJ-HCC-5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 细胞周期蛋白 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 64kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TPTE |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: TPTE is a 551 amino acid multi-pass membrane protein belonging to the PTEN-related family that is exclusively expressed in the testis and localizes to the plasma membrane in humans. The gene encoding TPTE is present in multiple copies in the human genome, some of which may be pseudogenes. TPTE contains one C2 tensin-type domain and one phosphatase tensin-type domain but, in humans, it does not exhibit phosphatase activity. However, the mouse ortholog (PTEN2) is a functional 3-phosphoinositide phosphatase that localizes to the Golgi apparatus and plays a possible role in signal transduction. In humans, four isoforms, namely TPTEå, TPTE∫, TPTE© and TPTE∂, are produced by alternative splicing of this gene. Function: Could be involved in signal transduction. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Exclusively expressed in testis. Similarity: Contains 1 C2 tensin-type domain. Contains 1 phosphatase tensin-type domain. Database links: Entrez Gene: 7179 Human Omim: 604336 Human SwissProt: P56180 Human Unigene: 122986 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
TPTE是一种551氨基酸多通道膜蛋白，属于PTEN相关家族，在睾丸中特异表达，定位于人的质膜。编码TPTE的基因存在于人类基因组中的多个拷贝中，其中一些可能是假基因。TPTE包含一个C2张力蛋白型结构域和一个磷酸酶张力蛋白类型域，但在人类中，它不具有磷酸酶活性。然而，小鼠同源基因（PTEN2）是一种功能性的3-磷酸肌醇磷酸酶，定位于高尔基体，并在信号转导中发挥可能的作用。在人类中，通过该基因的选择性剪接，产生了四种亚型，即TpTe、TpTe、TpTe和TpTe。