C21orf2,21号染色体开放阅读框2抗体

产品编号HZ-9977R
英文名称C21orf2
中文名称21号染色体开放阅读框2抗体
别 名A2 antibody C21orf HUMF09G8.5; Chromosome 21 open reading frame 2; Hypothetical protein LOC755; Nuclear encoded mitochondrial protein cDNA A2 YF5; Uncharacterized protein C21orf2; YF 5; YF5; YF5/A2 antibody.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 发育生物学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
C21orf2,21号染色体开放阅读框2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量28kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human C21orf2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
C21orf2,21号染色体开放阅读框2抗体PubMedPubMed
产品介绍background:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf2 gene product has been provisionally designated C21orf2 pending further characterization.

Function:
May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization.

Subunit:

Similarity:
Contains 3 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
To C.elegans F09G8.5.

Database links:
Entrez Gene: 755 Human
Entrez Gene: 67884 Mouse
Omim: 603191 Human
SwissProt: O43822 Human
SwissProt: Q8C6G1 Mouse
Unigene: 517331 Human

C21orf2,21号染色体开放阅读框2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.