FITC标记的新型核蛋白质1抗体
产品名称： FITC标记的新型核蛋白质1抗体
英文名称： Anti-NNP1/FITC
产品编号： HZ-9300R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-NNP1/FITC Conjugated antibody
FITC标记的新型核蛋白质1抗体
| 产品编号 | bs-9300R-FITC |
| 英文名称 | Anti-NNP1/FITC |
| 中文名称 | FITC标记的新型核蛋白质1抗体 |
| 别 名 | NNP 1; NNP-1; NNP1; Nnp1 homolog nucleolar protein; Novel nuclear protein 1; Nucleolar protein Nop52; Protein NNP 1; Protein NNP1; Ribosomal RNA processing 1 homolog; Ribosomal RNA processing protein 1 homolog A; rrp1; RRP1 like protein; RRP1-like protein; RRP1_HUMAN; RRP1A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞周期蛋白 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NNP1/RRP1 like protein |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Novel nuclear protein 1 (NNP-1), also known as RRP1-like protein or Nucleolar protein Nop52, is a 461 amino acid protein belonging to the RRP1 family. Localized to the nucleolus, NNP-1 has simian virus 40-type and bipartite nuclear localization signals and four coiled-coil domains within its C-terminal region. NNP-1 has been found to play an important role in the generation of 28S rRNA in the late processing steps of ribosome biogenesis. At the end of mitosis, nucleolar proteins assemble in a sequential order during the rebuilding of the nucleolus. NNP-1 assembles after Fibrillarin and C23, and simultaneously with B23 and POP1 in the prenucleolar body pathway. Function: Plays a critical role in the generation of 28S rRNA. Subunit: Interacts with C1QBP. Subcellular Location: Nucleus, nucleolus. Tissue Specificity: Ubiquitously expressed in fetal and adult tissues. Similarity: Belongs to the RRP1 family. Database links: Entrez Gene: 23076 Human Entrez Gene: 72462 Mouse Entrez Gene: 309673 Rat Omim: 610654 Human SwissProt: Q14684 Human SwissProt: Q91YK2 Mouse Unigene: 654727 Human Unigene: 54275 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
新的核蛋白1（NNP-1），又称RRP1样蛋白或核仁蛋白Nop52，是属于RRP1家族的461个氨基酸蛋白质。NNP-1定位于核仁，具有猴病毒40型和二分核定位信号和四个卷曲螺旋结构域在其C-末端区域。NNP-1在核糖体生物合成的后期处理过程中，对产生8S rRNA有重要作用。在有丝分裂结束时，核仁蛋白在核仁重建过程中按顺序排列。NNP-1在纤颤蛋白和C23后聚集，同时与B23和POP1一起在前核体通路中聚集。