FITC标记的G蛋白偶联受体35抗体
产品名称： FITC标记的G蛋白偶联受体35抗体
英文名称： Anti-GPR35/FITC
产品编号： HZ-13533R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GPR35/FITC Conjugated antibody
FITC标记的G蛋白偶联受体35抗体
| 英文名称 | Anti-GPR35/FITC |
| 中文名称 | FITC标记的G蛋白偶联受体35抗体 |
| 别 名 | GPCR GPR35; G protein coupled receptor 35; GPR 35; GPCR 35; GPR35; KYNA receptor; Kynurenic acid receptor; Probable G protein coupled receptor 35; Probable G protein coupled receptor GPR35. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR35 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR35 (G protein-coupled receptor 35) is a 309 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. Expressed in adult and fetal tissues, including lung, pancreas, colon and intestine, GPR35 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell. Function: G protein-coupled receptors (GPRs, or GPCRs) contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GPR35 is a member of this family and is an orphan receptor. GPR35 expression was reported only in rat intestine (O'Dowd et al., 1998) by Northern hybridization; however, another study showed that GPR35 is expressed widely, including pancreatic islets and skeletal muscle, with higher levels in adult lung, small intestine, colon, and stomach. Subcellular Location: Cell membrane; Multi-pass membrane protein. Database links: Entrez Gene: 2859 Human Omim: 602646 Human SwissProt: Q9HC97 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
G蛋白偶联受体(GPR)又称七种跨膜受体、七肽受体或七肽甲基转移酶(7TM)受体，由在许多不同的刺激-反应途径中起作用的蛋白超家族组成。G蛋白偶联受体将细胞外信号翻译成细胞内信号（G蛋白激活），并对多种信号分子作出反应，如激素和神经递质。GPR35(G蛋白偶联受体35)是属于G蛋白偶联受体1家族的309个氨基酸多通道膜蛋白。GPR35表达于成人和胎儿组织，包括肺、胰腺、结肠和肠，其作为孤儿受体发挥作用，该受体被认为在整个细胞中的信号传导事件中发挥作用。