FITC标记的蛋白质精氨酸亚型1抗体
产品名称： FITC标记的蛋白质精氨酸亚型1抗体
英文名称： Anti-PADI1 / PAD1/FITC
产品编号： HZ-20000R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PADI1 / PAD1/FITC Conjugated antibody
FITC标记的蛋白质精氨酸亚型1抗体
| 英文名称 | Anti-PADI1 / PAD1/FITC |
| 中文名称 | FITC标记的蛋白质精氨酸亚型1抗体 |
| 别 名 | HPAD10; Padi1; PADI1_HUMAN; PDI; PDI1; Peptidylarginine deiminase I; protein arginine deiminase type I; Protein-arginine deiminase type I; Protein-arginine deiminase type-1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 75kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PADI1 / PAD1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] Function: Catalyzes the deimination of arginine residues of proteins. Subcellular Location: Cytoplasm. Tissue Specificity: Epidermis, prostate, testis, placenta, spleen and thymus. Similarity: Belongs to the protein arginine deiminase family. Database links: Entrez Gene: 29943 Human Omim: 607934 Human SwissProt: Q9ULC6 Human Unigene: 412941 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码肽基精氨酸脱亚胺酶家族的成员，该酶通过在钙离子存在下将精氨酸残基转化为瓜氨酸来催化蛋白质翻译后的脱亚胺作用。家族成员具有不同的底物特异性和组织特异性表达模式。I型酶参与表皮分化的晚期阶段，在那里它消除丝蛋白和角蛋白K1，角蛋白K1维持角质层的水合作用，因此皮肤屏障功能。这种酶也可能在毛囊形成中起作用。该基因与其他四个同源基因一起存在。