FITC标记的载脂蛋白C3抗体
产品名称： FITC标记的载脂蛋白C3抗体
英文名称： Anti-APOC3/FITC
产品编号： HZ-4741R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-APOC3/FITC Conjugated antibody
FITC标记的载脂蛋白C3抗体
| 产品编号 | bs-4741R-FITC |
| 英文名称 | Anti-APOC3/FITC |
| 中文名称 | FITC标记的载脂蛋白C3抗体 |
| 别 名 | APO C3; Apo CIII; Apo-CIII; APOC 3; ApoC III; ApoC-III; APOC3; APOC3_HUMAN; ApoCIII; Apolipoprotein C III; Apolipoprotein C-III; Apolipoprotein C3; ApolipoproteinCIII; MGC150353. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 心血管 细胞生物 免疫学 信号转导 脂蛋白 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 9kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human APOC3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in apoC-III levels induces the development of hypertriglyceridemia. Function: Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles. Subcellular Location: Secreted. Tissue Specificity: Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine. Post-translational modifications: O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan. DISEASE: Hyperalphalipoproteinemia 2 (HALP2) [MIM:614028]: A condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the apolipoprotein C3 family. Database links: Entrez Gene: 345 Human Entrez Gene: 11814 Mouse Entrez Gene: 24207 Rat Omim: 107720 Human SwissProt: P02656 Human SwissProt: P33622 Mouse SwissProt: P06759 Rat Unigene: 73849 Human Unigene: 390161 Mouse Unigene: 195323 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
载脂蛋白C-III是一种极低密度脂蛋白（VLDL）蛋白。它抑制脂蛋白脂肪酶和肝脂肪酶，被认为延迟了富含甘油三酯颗粒的分解代谢。APOCⅢ水平的升高诱导高甘油三酯血症的发生。