FITC标记的卷曲螺旋结构域蛋白69抗体
产品名称： FITC标记的卷曲螺旋结构域蛋白69抗体
英文名称： Anti-CCDC69/FITC
产品编号： HZ-6919R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CCDC69/FITC Conjugated antibody
FITC标记的卷曲螺旋结构域蛋白69抗体
| 产品编号 | bs-6919R-FITC |
| 英文名称 | Anti-CCDC69/FITC |
| 中文名称 | FITC标记的卷曲螺旋结构域蛋白69抗体 |
| 别 名 | CCD69_HUMAN; ccdc69; Coiled coil domain containing 69; Coiled-coil domain-containing protein 69. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Dog, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCDC69 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC69 (Coiled-coil domain-containing protein 69) is a 296 amino acid protein that is encoded by a gene which maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Tissue Specificity: Lymph, lymphoma. Database links: UniProtKB/Swiss-Prot: A6NI79.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
卷曲螺旋结构域是在蛋白质中发现的结构基序，涉及多种多样的生物学功能，如基因表达调控、细胞分裂、膜融合和药物挤出和递送。CCDC9（卷曲螺旋结构域含有蛋白质69）是由296个氨基酸编码的蛋白质，该基因被映射到人类染色体5，其包含1亿8100万个碱基对，并包含人类基因组的近6%。5号染色体通过ECRC8基因和家族性腺瘤性息肉病通过腺瘤性息肉病（APC）肿瘤抑制基因与Coojayne综合征相关。Treacher Collins综合征也是5号染色体相关的，是由TCOF1基因内的插入或缺失引起的。第5号染色体的P臂缺失导致CRI - Douter综合征，而Q臂或5号染色体的缺失在治疗相关的急性髓性白血病和骨髓增生异常综合征中是常见的。