KBTBD10,BTB-kelch蛋白家族10抗体-抗体-抗体-生物在线
上海沪震实业有限公司
KBTBD10,BTB-kelch蛋白家族10抗体

KBTBD10,BTB-kelch蛋白家族10抗体

商家询价

产品名称: KBTBD10,BTB-kelch蛋白家族10抗体

英文名称: Anti-KBTBD10 antibody

产品编号: HZ-8044R

产品价格: null

产品产地: 中国/美国

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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KBTBD10,BTB-kelch蛋白家族10抗体

产品编号HZ-8044R
英文名称KBTBD10
中文名称BTB-kelch蛋白家族10抗体
别 名cb52; fb24f05; fc15e07; Gm112; KBTBD10; Kel like protein 23; Kelch related protein 1; KRP1; MGC143407; Sarcosin; sbcb52; wufb24f05; wufc15e07; KBTBA_HUMAN.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 发育生物学 信号转导 细胞凋亡 转录调节因子 细胞骨架
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
KBTBD10,BTB-kelch蛋白家族10抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量68kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human KBTBD10
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
KBTBD10,BTB-kelch蛋白家族10抗体PubMedPubMed
产品介绍background:
Sarcosin contains 1 BTB (POZ) domain and is required for pseudopod elongation in transformed cells. Sarcosin mRNA is up-regulated by less than two folds in the heart in human patients with HCM.

Function:
Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subunit:
Interacts with NRAP (By similarity). Part of a complex that contains CUL3, RBX1 and KBTBD10.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection, ruffle. Note=Predominantly cytoplasmic but can co-localize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia.

Post-translational modifications:
Ubiquitinated and probably targeted for proteasome-independent degradation.

KBTBD10,BTB-kelch蛋白家族10抗体Similarity:
Contains 1 BTB (POZ) domain.
Contains 5 Kelch repeats.

Database links:
UniProtKB/Swiss-Prot: O60662.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.