FITC标记的核酸内切酶G抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的核酸内切酶G抗体

FITC标记的核酸内切酶G抗体

商家询价

产品名称: FITC标记的核酸内切酶G抗体

英文名称: Anti-Endo G/FITC

产品编号: HZ-2800R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-Endo G/FITC Conjugated antibody

FITC标记的核酸内切酶G抗体

 

英文名称 Anti-Endo G/FITC
中文名称 FITC标记的核酸内切酶G抗体
别    名 EndoG; Endonuclease G; Endonuclease G mitochondrial; EndonucleaseG; FLJ27463; ENDOG; NUCG_HUMAN; Endo G.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  染色质和核信号  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Endo G
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008].

Function:
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.

Subunit:
Homodimer.

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the DNA/RNA non-specific endonuclease family.

Database links:

Entrez Gene: 2021 Human

Entrez Gene: 13804 Mouse

Entrez Gene: 362100 Rat

Omim: 600440 Human

SwissProt: Q14249 Human

SwissProt: O08600 Mouse

Unigene: 224137 Human

Unigene: 474473 Mouse

Unigene: 3807 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

由该基因编码的蛋白质是定位在线粒体中的核编码核酸内切酶。编码的蛋白质广泛分布于动物体内,并在GC通道裂解DNA。这种蛋白质能够产生由DNA聚合酶γ启动线粒体DNA复制所需的RNA引物。[ RefSeq,JUL 2008 ]提供。