FITC标记的可溶性附着蛋白α-SNAP抗体
产品名称： FITC标记的可溶性附着蛋白α-SNAP抗体
英文名称： Anti-Alpha SNAP/FITC
产品编号： HZ-12465R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Alpha SNAP/FITC Conjugated antibody
FITC标记的可溶性附着蛋白α-SNAP抗体
| 英文名称 | Anti-Alpha SNAP/FITC |
| 中文名称 | FITC标记的可溶性附着蛋白α-SNAP抗体 |
| 别 名 | Alpha soluble NSF attachment protein; Alpha-soluble NSF attachment protein; N ethylmaleimide sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; NAPA; SNAA_HUMAN; SNAP alpha; SNAP alpha; SNAP-alpha; SNAPA. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Alpha SNAP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Subunit: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity). Subcellular Location: Membrane; Peripheral membrane protein. Similarity: Belongs to the SNAP family. Database links: Entrez Gene: 518407 Cow Entrez Gene: 8775 Human Entrez Gene: 108124 Mouse Entrez Gene: 140673 Rat Omim: 603215 Human SwissProt: P81125 Cow SwissProt: P54920 Human SwissProt: Q9DB05 Mouse SwissProt: P54921 Rat Unigene: 126938 Human Unigene: 727492 Human Unigene: 104540 Mouse Unigene: 431371 Mouse Unigene: 31745 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
合成素原本被认为是对接蛋白，但最近被归类为锚定蛋白，锚定蛋白将自身锚定到细胞膜的细胞质表面。已证明突触蛋白与参与胞吐的多种蛋白结合，包括VAMP(囊泡相关膜蛋白)、NSF(N-乙基马来酰亚胺敏感因子)、SNAP 25(突触体相关蛋白25kDa)、SNAPs(可溶性NSF附着蛋白)和突触结合蛋白。VAMP（也称为突触突触蛋白），包括VAMP-1和VAMP-2，以及突触素，一种可以抑制胞吐的蛋白质，是囊泡蛋白。