Bcl2A1,BCL2相关蛋白A1抗体

产品编号HZ-20163R
英文名称Bcl2A1
中文名称BCL2相关蛋白A1抗体
别 名ACC 1; ACC 2; B2LA1_HUMAN; Bcl 2 related protein A1; Bcl-2-like protein 5; Bcl-2-related protein A1; BCL2 related protein A1; Bcl2-L-5; BCL2A1; BCL2L5; BFL1; GRS; HBPA1; Hematopoietic BCL2 related protein A1; Hemopoietic specific early response protein; Hemopoietic-specific early response protein; Protein BFL 1; Protein BFL-1; Protein GRS.
说 明 书0.1ml 0.2ml
研究领域细胞生物 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,
Bcl2A1,BCL2相关蛋白A1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse Bcl2A1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Bcl2A1,BCL2相关蛋白A1抗体PubMedPubMed
产品介绍Function:
Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.

Subunit:
Interacts directly with BAK1, BID, BMF and BBC3. Interacts directly with BCL2L11/BIM. Interacts with BAX isoform Sigma.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.

Similarity:
Belongs to the Bcl-2 family.

Gene ID:
12044

Bcl2A1,BCL2相关蛋白A1抗体Database links:
Entrez Gene: 597 Human
Entrez Gene: 12044 Mouse
Entrez Gene: 170929 Rat
Omim: 601056 Human
SwissProt: Q16548 Human
SwissProt: Q07440 Mouse
Unigene: 227817 Human
Unigene: 425593 Mouse
Unigene: 479217 Mouse
Unigene: 19770 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Tissue/cell: rat spleen tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-Bcl2A1 Polyclonal Antibody, Unconjugated(HZ-20163R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining