FITC标记的FAM189A1蛋白抗体
产品名称： FITC标记的FAM189A1蛋白抗体
英文名称： Anti-FAM189A1/FITC
产品编号： HZ-14767R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FAM189A1/FITC Conjugated antibody
FITC标记的FAM189A1蛋白抗体
| 英文名称 | Anti-FAM189A1/FITC |
| 中文名称 | FITC标记的FAM189A1蛋白抗体 |
| 别 名 | F1891_HUMAN; FAM189A1; KIAA0574; Protein FAM189A1; TMEM228; Transmembrane protein 228. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Guinea Pig, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 57kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM189A1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: FAM189A1 is a 539 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding FAM189A1 maps to human chromosome 15, which encodes more than 700 genes and is made up of approximately 106 million base pairs. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. Subcellular Location: Membrane. Similarity: Belongs to the FAM189 family. Database links: Entrez Gene: 23359 Human SwissProt: O60320 Human Unigene: 383564 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
FAM189A1是一种539氨基酸多通道膜蛋白，以两种交替剪接的异构体存在。编码FAM189A1的基因定位于人类染色体15，该染色体编码700多个基因，由大约1.06亿个碱基对组成。Angelman和Prader Willi综合征与15q11-q13区域的功能丧失或基因缺失有关。对于Angelman综合征，这种丢失是由于母体15q11-q13编码的UBE3A基因在大脑中通过染色体缺失或突变而失活造成的。在Prader-Willi综合征的病例中，15号染色体的父本拷贝中有一部分或完全缺失。Tay-Sachs病是与15号染色体编码的HEXA基因突变相关的致死性疾病。MfFe综合征通过FBN1基因与15号染色体相关。