PDGFRA/CEN4p FISH Probe
产品名称： PDGFRA/CEN4p FISH Probe
英文名称： PDGFRA/CEN4p FISH Probe
产品编号： FG0087
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - PDGFRA
Approximately 240kb
Texas Red
4q12
- Probe 2:
Size:
Fluorophore:
Location: - CEN4p
Approximately 560kb
FITC
4p13
- Probe Gap:
- The gap between two probes is approximately 9200 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Human lung squamous cell carcinoma (FFPE) stained with PDGFRA/CEN4p FISH Probe. Human lung squamous cell carcinoma showed no PDGFRA gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 5156
- Gene Name:
- PDGFRA
- Gene Alias:
- CD140A,MGC74795,PDGFR2,Rhe-PDGFRA
- Gene Description:
- platelet-derived growth factor receptor, alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq
- Other Designations:
- FIP1L1/PDGFRA fusion protein,platelet-derived growth factor receptor alpha,rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
- Related Disease