FITC标记的膜相关环指蛋白7抗体
产品名称： FITC标记的膜相关环指蛋白7抗体
英文名称： Anti-MARCH7/FITC
产品编号： HZ-9341R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MARCH7/FITC Conjugated antibody
FITC标记的膜相关环指蛋白7抗体
| 产品编号 | bs-9341R-FITC |
| 英文名称 | Anti-MARCH7/FITC |
| 中文名称 | FITC标记的膜相关环指蛋白7抗体 |
| 别 名 | AXO; AXOT; Axotrophin; E3 ubiquitin-protein ligase MARCH7; MARCH VII; MARCH-VII; March7; MARH7_HUMAN; Membrane associated RING CH protein VII; Membrane associated ring finger (C3HC4) 7 E3 ubiquitin protein ligase; membrane associated ring finger C3HC4 7; Membrane associated RING finger protein 7; Membrane-associated RING finger protein 7; Membrane-associated RING-CH protein VII; RING finger protein 177; RNF177. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 干细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 78kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MARCH7/Axotrophin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Axotrophin is a stem cell gene that encodes a protein which is involved in T lymphocyte regulation (especially in regulating the proliferation) and leukemia inhibitory factor (LIF) release. LIF is a neuropoietic cytokine that is important for stem cell regulation and thymocyte stimulation. Both Axotrophin and LIF are linked to transplantation intolerance. Axotrophin is also involved in corpus callosum differentiation and may play a role in glial cell line-derived neurotrophic factor (GDNF)-dependent sensory neuron survival in the substantia gelatinosa of the adult spinal cord. Axotrophin is primarily expressed in the hippocampus, cortex, purkinje and granule cells of the cerebellum. Function: E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Similarity: Contains 1 RING-CH-type zinc finger. Database links: Entrez Gene: 64844 Human Entrez Gene: 57438 Mouse Entrez Gene: 311059 Rat Omim: 613334 Human SwissProt: Q9H992 Human SwissProt: Q9WV66 Mouse SwissProt: Q5R9W2 Orangutan SwissProt: Q5XI50 Rat Unigene: 529272 Human Unigene: 260635 Mouse Unigene: 117620 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
AxoPurin是一种编码T淋巴细胞调控（尤其是调节增殖）和白血病抑制因子（LIF）释放的蛋白质的干细胞基因。LIF是神经干细胞因子，对干细胞调节和胸腺细胞刺激具有重要意义。Axotrophin和LIF都与移植不耐受有关。Axotrophin还参与胼胝体分化，并可能在胶质细胞系来源的神经营养因子（GDNF）依赖性感觉神经元存活的作用在成人脊髓胶凝质。Axotrophin主要在小脑的海马、皮质、浦肯野和颗粒细胞中表达。