COPZ2,衣壳蛋白-ζ2抗体

产品编号HZ-13983R
英文名称COPZ2
中文名称衣壳蛋白-ζ2抗体
别 名Coatomer protein complex, subunit zeta 2; Coatomer subunit zeta-2; MGC23008; Nonclathrin coat protein zeta-COP; Zeta-2 COP; COPZ2_HUMAN; Zeta-2-coat protein; zeta2-COP.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 转运蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Rabbit, Sheep,
COPZ2,衣壳蛋白-ζ2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human COPZ2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
COPZ2,衣壳蛋白-ζ2抗体PubMedPubMed
产品介绍background:
This gene encodes a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. This gene is similar to a related family member, and the two encoded proteins form distinct isotypes of the coatomer protein complex. [provided by RefSeq, Jul 2008]

Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle; COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.

Gene ID:
51226

Database links:
Entrez Gene: 51226 Human
Entrez Gene: 56358 Mouse
SwissProt: Q9P299 Human
SwissProt: Q9JHH9 Mouse

COPZ2,衣壳蛋白-ζ2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.