BUB3抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
BUB3抗体

BUB3抗体

商家询价

产品名称： BUB3抗体

英文名称： BUB3Antibody

产品编号： XY 10123-2-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 BUB3抗体

Applications
In-house applications ELISA, IF     Application not tested? Please see our Guarantee.
Species specificity Human, mouse, rat; other species not tested.
Images
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  • 10123-2-AP;HepG2Immunofluorescent analysis of HepG2 cells, using BUB3 antibody 10123-2-AP at 1:100 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
Positive IF detected in HepG2
Recommended dilution IF : 1:20-1:200
 BUB3抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen BUB3 fusion protein ag0167 Full name Budding uninhibited by benzimidazoles 3 homolog (yeast)
Calculated molecular
weight		 37 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC005138 Gene ID (NCBI) 9184
Gene symbol BUB3 Synonyms BUB3, hBUB3, BUB3L
Background BUB3抗体

BUB3 is a conserved component of the mitotic spindle assembly complex and is an essential compent of spindle-assembly checkpoint (SAC) signaling that operates during early embryogenesis. BUB3 null embryos treated with a spindle-depolymerising agent fail to arrest in metaphase and show an increase in mitotic disarray. In mitosis, the SAC prevents anaphase onset until all chromosomes have been attached to the spindle microtubules and aligned correctly at the equatorial metaphase plate. BUB3 is involved in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments in mammalian oocyte meiosis. BUB3抗体

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