RNF6抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
RNF6抗体

RNF6抗体

商家询价

产品名称： RNF6抗体

英文名称： Antibody

产品编号： XY20437-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
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 ADCY7抗体Applications

In-house applications ELISA, WB, IF, IP     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
Prev1NextView more validation data
  • 20437-1-AP;mouse testis tissuemouse testis tissue were subjected to SDS PAGE followed by western blot with 20437-1-AP(RNF6 antibody) at dilution of 1:800
  • 20437-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using RNF6 antibody 20437-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 20437-1-AP;mouse testis tissueIP Result of anti-RNF6 (IP:20437-1-AP, 4ug; Detection:20437-1-AP 1:800) with mouse testis tissue lysate 4000ug.
Positive WB detected in Mouse testis tissue, PC-3 cells
Positive IP detected in Mouse testis tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IF : 1:10-1:100
 ADCY7抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen RNF6 fusion protein ag14209 Full name Ring finger protein (C3H2C3 type) 6
Calculated molecular
weight		 685aa,78 kDa Observed molecular 
weight		 78 kDa
GenBank accession 
number		 BC034688 Gene ID (NCBI) 6049
Gene symbol RNF6 Synonyms DKFZp686P0776, RNF6, SPG2
Background ADCY7抗体

RNF6 was firstly cloned in a genetic study of chromosomal rearrangements in myeloproliferative disorders, mapping to chromosome 13q12.12 [PMID:10331950]. It containing a coiled-coil domain at the N-terminus, and a RING-H2 finger at the C-terminus which is responsible for its ubiquitin ligase activity. It also activate Inha gene expression by participating in a protein complex binding to the promoter region [PMID:11971979]. In addition, LIMK1 is a substrate of RNF6 and the RNF6-induced LIMK1 polyubiquitination is mediated via K48 of ubiquitin and leads to proteasomal degradation of the kinase [PMID:16204183]. ADCY7抗体

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XY904Hu21 组蛋白脱乙酰基酶4(HDAC4)单克隆抗体 Monoclonal Antibody to Histone Deacetylase 4 (HDAC4) Homo sapiens (Hukl)

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