EFHA2,EFHA2蛋白抗体

产品编号HZ-14518R
英文名称EFHA2
中文名称EFHA2蛋白抗体
别 名EF-HA2; 2900075B16Rik; DKFZp313A0139; EF hand domain family A2; EF hand domain family member A2; EF-hand domain-containing family member A2; Efha2; MICU3_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 结合蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
EFHA2,EFHA2蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量61kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EFHA2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EFHA2,EFHA2蛋白抗体PubMedPubMed
产品介绍background:
The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HB (EF-hand domain-containing family member B) is a 831 amino acid protein that contains two EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. There are three isoforms of EF-HB that are produced as a result of alternative splicing events. The gene encoding EF-HB is located on human chromosome three,which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Other well-studied calcium binding proteins that contain EF-hand motifs include calmodulin (CaM), Troponin C, myosin regulatory light chain (MYL) and S-100 proteins

Function:
May play a role in mitochondrial calcium uptake (By similarity).

Subcellular Location:
Mitochondrion (By similarity). Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:

EFHA2,EFHA2蛋白抗体Similarity:
Contains 2 EF-hand domains.

Gene ID:
151651

Database links:
Entrez Gene: 151651 Human
SwissProt: Q8N7U6 Human
Unigene: 120196 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.