CFH (Human) Recombinant Protein (P02)
产品名称: CFH (Human) Recombinant Protein (P02)
英文名称: CFH (Human) Recombinant Protein (P02)
产品编号: H00003075-P02
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CFH full-length ORF ( AAH20687, 1 a.a. - 195 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MLLLINVVLTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSYMVFCISY
- Theoretical MW (kDa):
- 47.19
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3075
- GeneBank Accession#:
- BC020687
- Protein Accession#:
- AAH20687
- Gene Name:
- CFH
- Gene Alias:
- ARMD4,ARMS1,CFHL3,FH,FHL1,HF,HF1,HF2,HUS,MGC88246
- Gene Description:
- complement factor H
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- H factor 1 (complement),H factor 2 (complement),OTTHUMP00000033598,age-related maculopathy susceptibility 1,beta-1-H-globulin,beta-1H,complement factor H, isoform b,factor H,factor H-like 1
- Gene Pathway
- Related Disease
- Alport syndrome
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Ataxia Telangiectasia
- Ataxia telangiectasia
- Atherosclerosis
- Atherosclerosis
- Atrophy
- Blindness
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Carotid Artery Diseases
- Cerebrovascular Accident
- Chlamydia Infections
- Chlamydophila Infections
- Choroid Diseases