C20orf11,20号染色体开放阅读框11抗体

产品编号HZ-9689R
英文名称C20orf11
中文名称20号染色体开放阅读框11抗体
别 名Chromosome 20 open reading frame 11; CT011_HUMAN; Protein C20orf11; Twa1; Two hybrid associated protein 1; Two hybrid-associated protein 1 with Ran BP-M; Two hybrid associated protein 1 with RanBPM; Two hybrid-associated protein 1 with RanBPM.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Horse,
C20orf11,20号染色体开放阅读框11抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human TWA1/C20orf11
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
C20orf11,20号染色体开放阅读框11抗体PubMedPubMed
产品介绍background:
TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.

Subunit:
Interacts with RANBP9. Part of a complex consisting of RANBP9, MKLN1 and GID8.

Subcellular Location:
Nucleus.

C20orf11,20号染色体开放阅读框11抗体Similarity:
Belongs to the GID8 family.
Contains 1 CTLH domain.
Contains 1 LisH domain.

Database links:
Entrez Gene: 54994 Human
Omim: 611625 Human
SwissProt: Q9NWU2 Human
SwissProt: Q9D7M1 Mouse
Unigene: 353013 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.