CYP2A13 Pre-design Chimera RNAi
产品名称： CYP2A13 Pre-design Chimera RNAi
英文名称： CYP2A13 Pre-design Chimera RNAi
产品编号： H00001553-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
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- Specification
- Product Description:
- Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 13 (CYP2A13), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000766
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 1553
- Gene Name:
- CYP2A13
- Gene Alias:
- CPAD,CYP2A
- Gene Description:
- cytochrome P450, family 2, subfamily A, polypeptide 13
- Omim ID:
- 608055
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq
- Other Designations:
- cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13
- Related Disease
- Adenocarcinoma
- Carcinoma
- Carcinoma, Squamous Cell
- Disease Susceptibility
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Laryngeal Neoplasms
- Leiomyomatosis
- Lung Neoplasms
- Mouth Neoplasms
- Neoplasms
- Pancreatic Neoplasms
- Pharyngeal Neoplasms
- Precancerous Conditions
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Uterine Neoplasms