TNFRSF11A monoclonal antibody, clone 64C1385.1
产品名称： TNFRSF11A monoclonal antibody, clone 64C1385.1
英文名称： TNFRSF11A monoclonal antibody, clone 64C1385.1
产品编号： MAB0091
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant TNFRSF11A.
- Immunogen:
- Recombinant protein corresponding to extracellular region of human RANK.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Immunoprecipitation
- Detection of RANK in RAW cells. Lane 1. Western blot detection of RANK in RAW, a mouse cell line. Lane 2 & 3. IP/Western blot analysis of RANK. RANK protein from RAW cell lysate was immunoprecipitated either with control antibody (lane 2) or TNFRSF11A monoclonal antibody, clone 64C1385.1 (Cat # MAB0091) (lane 3) , the immunopricipitated proteins were resolved on SDS-PAGE. RANK was detected by western blot using TNFRSF11A monoclonal antibody, clone 64C1385.1 (Cat # MAB0091) .
- Entrez GeneID:
- 8792
- Gene Name:
- TNFRSF11A
- Gene Alias:
- CD265,FEO,LOH18CR1,ODFR,OFE,OPTB7,OSTS,PDB2,RANK,TRANCER
- Gene Description:
- tumor necrosis factor receptor superfamily, member 11a, NFKB activator
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells. [provided by RefSeq
- Other Designations:
- loss of heterozygosity, 18, chromosomal region 1,osteoclast differentiation factor receptor,receptor activator of nuclear factor-kappa B,tumor necrosis factor receptor superfamily, member 11a,tumor necrosis factor receptor superfamily, member 11a, activat
- Gene Pathway
- Related Disease
- Acute Disease
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Bone Diseases, Metabolic
- Bone Resorption
- Cardiovascular Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fractures, Bone
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Lupus Erythematosus, Systemic
- Metabolic Syndrome X
- Neoplasms