FITC标记的13号染色体开放阅读框38抗体
产品名称： FITC标记的13号染色体开放阅读框38抗体
英文名称： Anti-C13orf38/FITC
产品编号： HZ-9613R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C13orf38/FITC Conjugated antibody
FITC标记的13号染色体开放阅读框38抗体
| 产品编号 | bs-9613R-FITC |
| 英文名称 | Anti-C13orf38/FITC |
| 中文名称 | FITC标记的13号染色体开放阅读框38抗体 |
| 别 名 | FLJ57222; Chromosome 13 open reading frame 38; CM038_HUMAN; FLJ13506; FLJ29024; Hypothetical protein LOC728591; RP11-251J8.1; UPF0594 protein C13orf38. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C13orf38/LOC728591 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The LOC728591 gene product has been provisionally designated LOC728591 pending further characterization. Similarity: Belongs to the CCDC169 family. Database links: Entrez Gene: 728591 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
包括13的人类DNA，染色体13包含大约1亿1400万个碱基对和400个基因。13号染色体上的关键肿瘤抑制基因包括乳腺癌易感基因BRCA2和RB1（视网膜母细胞瘤）基因。RB1编码一种关键的肿瘤抑制蛋白，当有缺陷时，它会导致视网膜的恶性生长，并被牵连在多种其他癌症中。与Tourtter综合征相关的基因SITRRK1在第13号染色体上。与大多数染色体一样，13号染色体部分或全部的多体性对发育有害，并降低存活率。Trisomy 13，也被称为PATAU综合征，是相当致命的，少数存活了一年的人患有永久性神经缺陷，难以进食和严重呼吸道感染的脆弱性。Lo78591基因产物已暂时指定为ROC728 591，有待进一步鉴定。