PCNA polyclonal antibody
产品名称： PCNA polyclonal antibody
英文名称： PCNA polyclonal antibody
产品编号： PAB12722
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant PCNA.
- Immunogen:
- Recombinant protein corresponding to human PCNA.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This antibody recognizes human PCNA.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (10% Proclin300)
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (0.1-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical staining of human tonsil tissue stained with PCNA polyclonal antibody (Cat # PAB12722) at 1 : 200 for 10 min at RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 5111
- Gene Name:
- PCNA
- Gene Alias:
- MGC8367
- Gene Description:
- proliferating cell nuclear antigen
- Omim ID:
- 176740
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
- Other Designations:
- DNA polymerase delta auxiliary protein,OTTHUMP00000030189,OTTHUMP00000030190,cyclin
- Interactome
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Colorectal Neoplasms
- Disease Progression
- DNA Damage
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Glioma
- Graft vs Host Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Laryngeal Neoplasms
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma