CHST5,碳水化合物磺基转移酶5抗体

产品编号HZ-13936R
英文名称CHST5
中文名称碳水化合物磺基转移酶5抗体
别 名Carbohydrate (N acetylglucosamine 6 O) sulfotransferase 5; Carbohydrate sulfotransferase 5; Chst5; CHST5_HUMAN; FLJ22167; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 4 alpha; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha; GlcNAc6ST 3; GlcNAc6ST-3; Gn6st-3; GST4 alpha; GST4-alpha; Intestinal GlcNAc-6-sulfotransferase; N acetylglucosamine 6 O sulfotransferase 3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
CHST5,碳水化合物磺基转移酶5抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量46kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CHST5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CHST5,碳水化合物磺基转移酶5抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]

Function:
Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates. However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for L-selectin. Its substrate specificity may be influenced by its subcellular location.

Subunit:

Subcellular Location:
Golgi apparatus membrane. Golgi membrane, early secretory pathway.

Tissue Specificity:
Predominantly expressed in small and large intestines and colon. Weakly expressed in lymphocytes. Not expressed in other tissues. Down-regulated in colonic adenocarcinomas.

CHST5,碳水化合物磺基转移酶5抗体Similarity:
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.

Gene ID:
23563

Database links:
Entrez Gene: 23563 Human
Omim: 604817 Human
SwissProt: Q9GZS9 Human
Unigene: 156784 Human
Unigene: 710689 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.