MARK4抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MARK4抗体

MARK4抗体

商家询价

产品名称： MARK4抗体

英文名称： MARK4Antibody

产品编号： XY20174-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
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 MARK4抗体

Applications
In-house applications ELISA, IHC, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 20174-1-AP;mouse testis tissuemouse testis tissue were subjected to SDS PAGE followed by western blot with 20174-1-AP(MARK4 antibody) at dilution of 1:500
  • 20174-1-AP;human kidneyImmunohistochemical of paraffin-embedded human kidney using 20174-1-AP(MARK4 antibody) at dilution of 1:50 (under 10x lens)
  • 20174-1-AP;human kidneyImmunohistochemical of paraffin-embedded human kidney using 20174-1-AP(MARK4 antibody) at dilution of 1:50 (under 40x lens)
Positive WB detected in Mouse testis tissue, L02 cells, PC-3 cells
Positive IHC detected in Human kidney tissue, human colon tissue, human gliomas tissue, human testis tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 MARK4抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen MARK4 fusion protein ag14013 Full name MAP/microtubule affinity-regulating kinase 4
Calculated molecular
weight		 752aa,83 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC009049 Gene ID (NCBI) 57787
Gene symbol MARK4 Synonyms FLJ90097, KIAA1860, MARK4, MARKL1, Nbla00650
Background MARK4抗体

MARK4(MAP/microtubule affinity-regulating kinase 4) is also named as KIAA1860, MARKL1 and belongs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. It is directly involved in microtubule organization in neuronal cells and may contribute to the pathological phosphorylation of tau in Alzheimer's disease and it also plays a role in hepatocellular carcinogenesis. This protein has 2 isoforms produced by alternative splicing with the molecular weight of 83 kDa and 75 kDa. MARK4 can exsit as 40-65 kDa forms in hippocampal homogenates from Alzheimer`s disease and non-demented elderly cases besides the full-length isoform 84 kDa. (PMID:24533944). MARK4抗体

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