NFASC (Human) Recombinant Protein (Q01)
产品名称: NFASC (Human) Recombinant Protein (Q01)
英文名称: NFASC (Human) Recombinant Protein (Q01)
产品编号: H00023114-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human NFASC partial ORF ( NP_001005388, 661 a.a. - 758 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- KDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNS
- Theoretical MW (kDa):
- 36.52
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 23114
- GeneBank Accession#:
- NM_001005388
- Protein Accession#:
- NP_001005388
- Gene Name:
- NFASC
- Gene Alias:
- DKFZp686P2250,FLJ46866,KIAA0756,NF,NRCAML
- Gene Description:
- neurofascin homolog (chicken)
- Omim ID:
- 609145
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined
- Other Designations:
- OTTHUMP00000065305,OTTHUMP00000065306,OTTHUMP00000065307,OTTHUMP00000065308,OTTHUMP00000065313,OTTHUMP00000065315,OTTHUMP00000065321,OTTHUMP00000065322,OTTHUMP00000065324,neurofascin
- Gene Pathway
- Related Disease