FITC标记的ATP依赖RNA解旋酶DDX50抗体
产品名称: FITC标记的ATP依赖RNA解旋酶DDX50抗体
英文名称: Anti-DDX50/FITC
产品编号: HZ-14231R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DDX50/FITC Conjugated antibody
FITC标记的ATP依赖RNA解旋酶DDX50抗体
英文名称 | Anti-DDX50/FITC |
中文名称 | FITC标记的ATP依赖RNA解旋酶DDX50抗体 |
别 名 | 4933429B04Rik; ATP-dependent RNA helicase DDX50; Ddx50; DDX50_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50; DEAD box protein 50; Gu beta; Gu-beta; GU2; GUB; MGC109605; MGC3199; Nucleolar protein Gu2; RH II; RH II/GuB. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 发育生物学 转录调节因子 转运蛋白 细胞分化 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 83kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DDX50 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. [provided by RefSeq, Jul 2008] Subcellular Location: Nucleus, nucleolus. Similarity: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Database links: Entrez Gene: 79009 Human Entrez Gene: 94213 Mouse Entrez Gene: 361848 Rat Omim: 610373 Human SwissProt: Q9BQ39 Human SwissProt: Q99MJ9 Mouse Unigene: 522984 Human Unigene: 114116 Mouse Unigene: 98470 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
死盒蛋白,其特征在于保守的基序ASP Glu ALA-ASP(死亡),是假定的RNA解旋酶。它们涉及许多涉及RNA二级结构改变的细胞过程,如翻译起始、核和线粒体剪接、核糖体和剪接体组装。基于它们的分布模式,这种死亡盒蛋白家族的一些成员被认为参与胚胎发生、精子发生和细胞生长和分裂。该基因编码可能参与核糖体RNA合成或处理的死盒酶。该基因和DDX21,也被称为RH-II/GUA,具有相似的基因组结构,并在10号染色体上串联排列,表明这两个基因是在进化过程中由基因复制产生的。该基因在2, 3号染色体和4号染色体上具有假基因。该基因的选择性剪接产生多个转录变体,但所有其他变体的全长性质,但一个尚未定义。[ RefSeq,JUL 2008 ]