重组小鼠白介素IL-22(白细胞介素22)
产品名称: 重组小鼠白介素IL-22(白细胞介素22)
英文名称: Recombinant Mouse Interleukin-22
产品编号: HZ0344
产品价格: 0
产品产地: 中国/上海
品牌商标: 沪震生物
更新时间: 2023-08-17T10:24:20
使用范围: null
- 联系人 : 鲍丽雯
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重组小鼠白介素IL-22(白细胞介素22)
中文名称:重组小鼠白介素IL-22(白细胞介素22)
英文名称:Recombinant Mouse Interleukin-22
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Leu34-Val179表达纯化而来。
IL-22质量控制:>95%(还原性SDS-PAGE)。
IL-22制剂:冻干品
IL-22保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-22复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-22:
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.
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