CSNK1E (Human) Recombinant Protein
产品名称: CSNK1E (Human) Recombinant Protein
英文名称: CSNK1E (Human) Recombinant Protein
产品编号: P5525
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Human CSNK1E (NP_001885.1, 1 a.a. - 348 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 68
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf21) expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 54 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: CKtide. ATP: 100 uM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 1454
- Protein Accession#:
- NP_001885.1
- Gene Name:
- CSNK1E
- Gene Alias:
- HCKIE,MGC10398
- Gene Description:
- casein kinase 1, epsilon
- Omim ID:
- 600863
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- CKI-epsilon,OTTHUMP00000063258,OTTHUMP00000063263,casein kinase 1 epsilon,casein kinase I epsilon
- Interactome
- Related Disease
- Amphetamine-Related Disorders
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Bipolar Disorder
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Chronobiology Disorders
- Depressive Disorder
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Genetic Predisposition to Disease
- Heroin Dependence
- Mood Disorders
- NARP
- Neoplasm Invasiveness
- Prostate cancer