FITC标记的延伸因子EF-1δ抗体
产品名称： FITC标记的延伸因子EF-1δ抗体
英文名称： Anti-EEF1D/FITC
产品编号： HZ-13055R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EEF1D/FITC Conjugated antibody
FITC标记的延伸因子EF-1δ抗体
| 英文名称 | Anti-EEF1D/FITC |
| 中文名称 | FITC标记的延伸因子EF-1δ抗体 |
| 别 名 | Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EEF1D; EF 1 delta; EF 1D; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Elongation factor 1-delta; Eukaryotic translation elongation factor 1 delta; Guanine nucleotide exchange protein. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 转运蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EEF1D |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 亱C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20亱C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 亱C. |
| 产品介绍 | background: This gene encodes a subunit of the elongation factor-1complex, which is responsible for the enzymatic delivery ofaminoacyl tRNAs to the ribosome. This subunit, delta, functions asguanine nucleotide exchange factor. It is reported that followingHIV-1 infection, this subunit interacts with HIV-1 Tat. Thisinteraction results in repression of translation of host cellproteins and enhanced translation of viral proteins. Severalalternatively spliced transcript variants encoding multipleisoforms have been found for this gene. Related pseudogenes havebeen defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided byRefSeq, Aug 2010]. Function: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. Subunit: EF-1 is composed of 4 subunits: alpha, beta, deltaisoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2. Subcellular Location: Isoform 2: Nucleus. Tissue Specificity: Isoform 2 is specifically expressed in brain,cerebellum and testis. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the EF-1-beta/EF-1-delta family. Database links: UniProtKB/Swiss-Prot: P29692.5 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
该基因编码伸长因子-1复合体的一个亚单位，该亚单位负责将氨基酰tRNA酶传递到核糖体。该亚基δ起着鸟嘌呤核苷酸交换因子的作用。据报道，随着HIV-1感染，该亚基与HIV-1 TAT相互作用。这种相互作用导致宿主细胞蛋白翻译的抑制和病毒蛋白翻译的增强。已经发现了多个选择性剪接转录变体编码多个异构体。相关的假基因已被定义在染色体1, 6, 7、9, 11, 13、17, 19。[由RefSEQ，AUG 2010提供。