DAPP1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
DAPP1 抗体

DAPP1 抗体

商家询价

产品名称： DAPP1 抗体

英文名称： DAPP1 Antibody

产品编号： XY14722-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 DAPP1 抗体

Applications
In-house applications ELISA, IHC, IF     Application not tested? Please see our Guarantee.
Species specificity Human, mouse, rat; other species not tested.
Images
Prev1NextView more validation data
  • 14722-1-AP;human liver cancerImmunohistochemical of paraffin-embedded human liver cancer using 14722-1-AP(DAPP1 antibody) at dilution of 1:100 (under 40x lens)
  • 14722-1-AP;human liver cancerImmunohistochemical of paraffin-embedded human liver cancer using 14722-1-AP(DAPP1 antibody) at dilution of 1:100 (under 10x lens)
  • 14722-1-AP;HelaImmunofluorescent analysis of Hela cells, using DAPP1 antibody 14722-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
Positive IHC detected in Human liver cancer
Positive IF detected in Hela
Recommended dilution IHC : 1:20-1:200
IF : 1:20-1:200
DAPP1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen InformationDAPP1 抗体
Immunogen DAPP1 fusion protein ag6459 Full name Dual adaptor of phosphotyrosine and 3-phosphoinositides
Calculated molecular
weight		 32 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC012924 Gene ID (NCBI) 27071
Gene symbol DAPP1 Synonyms DAPP1, BAM32, DKFZp667E0716, hDAPP1
Background

DAPP1 was identified as dual adaptor for phosphotyrosine and 3-phosphoinositides, a novel 280 amino acid protein which contains a putative myristoylation site at its N-terminus followed by a SH2 and a PH domain at its C-terminus (PMID: 10432293). DAPP1 is also referred to B cell adaptor molecule of 32 kDa (Bam32), and is expressed by B lymphocytes, but not T lymphocytes or nonhematopoietic cells. DAPP1/Bam32 was shown to regulate BCR signaling downstream of phosphatidylinositol 3-kinase (PI3K) (PMID: 10770799). Furthermore, DAPP1/Bam32 may server to integrate PI3K and Src kinase signaling to promote Rac-dependent B cell adhesive interactions important for antigen presentation function (PMID: 20495066).DAPP1 抗体

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