FITC标记的黑色素瘤相关抗原4抗体
产品名称： FITC标记的黑色素瘤相关抗原4抗体
英文名称： Anti-MAGEA4/FITC
产品编号： HZ-3645R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MAGEA4/FITC Conjugated antibody
FITC标记的黑色素瘤相关抗原4抗体
| 英文名称 | Anti-MAGEA4/FITC |
| 中文名称 | FITC标记的黑色素瘤相关抗原4抗体 |
| 别 名 | MAGE 4; MAGE-A4;MAGE 4 antigen; MAGE 41; MAGE 41 antigen; MAGE 4A; MAGE 4B; MAGE X2; MAGE X2 antigen; MAGE4; MAGE41; MAGE4A; MAGE4B; MAGEA 4; MAGEA4; Melanoma antigen family A 4; Melanoma associated antigen 4; Cancer/testis antigen 1.4; CT1.4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAGE-A4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]. Tissue Specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 4103 Human Entrez Gene: 17140 Mouse Entrez Gene: 689858 Rat Omim: 300175 Human SwissProt: P43358 Human Unigene: 37107 Human Unigene: 377097 Mouse Unigene: 218695 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
该基因是MAGEA基因家族的成员。该家族成员编码具有50至80%个序列同一性的蛋白质。MAGEA基因的启动子和第一外显子表现出相当大的变异性，这表明该基因家族的存在使得能够在不同转录控制下表达相同的功能。MAGEA基因聚集在XQ28染色体上。它们与某些遗传性疾病有关，如先天性角化不良。至少有四个编码相同蛋白质的变体已经被发现。[ RefSeq，JUL 2008 ]提供。