FITC标记的血型抗原前体蛋白抗体
产品名称: FITC标记的血型抗原前体蛋白抗体
英文名称: Anti-Blood Group Antigen Precursor/FITC
产品编号: HZ-7589R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-Blood Group Antigen Precursor/FITC Conjugated antibody
FITC标记的血型抗原前体蛋白抗体
英文名称 | Anti-Blood Group Antigen Precursor/FITC |
中文名称 | FITC标记的血型抗原前体蛋白抗体 |
别 名 | A transferase; Abo; ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase); ABO glycosyltransferase; B (A) alpha 1, 3 glactosyltransferase; B transferase; BGAT_HUMAN; Fucosylglycoprotein 3 alpha galactosyltransferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha N acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein fucosylgalactoside alpha galactosyltransferase; Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; GTB; Histo blood group A transferase; Histo blood group A2 transferase; Histo blood group ABO system transferase; Histo blood group B transferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 心血管 细胞生物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Chimpanzee, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 41kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Blood Group Antigen Precursor |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. Function: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. Post-translational modifications: The soluble form derives from the membrane form by proteolytic processing. Similarity: Belongs to the glycosyltransferase 6 family. Database links: Entrez Gene: 28 Human Entrez Gene: 80908 Mouse Entrez Gene: 65270 Rat Omim: 110300 Human SwissProt: P16442 Human SwissProt: P38649 Mouse SwissProt: Q9ET32 Rat Unigene: 654423 Human Unigene: 160386 Mouse Unigene: 112591 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码与第一个发现的血型系统ABO相关的蛋白质。哪一个等位基因存在于个体中决定血型。O’血型是由于在蛋白质的N-末端附近的胍基-258的缺失引起的,这导致了几乎完全不同的蛋白质的移码和翻译。具有A、B和AB等位基因的个体表达糖基转移酶活性,其将H抗原转化为A或B抗原。其它小等位基因已被发现。