HIF2A抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
HIF2A抗体

HIF2A抗体

商家询价

产品名称： HIF2A抗体

英文名称： HIF2AAntibody

产品编号： XY21911-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 HIF2A抗体

Applications
Tested Applications: ELISA
Specificity Reaction: Human; Other species are not tested.Please decide the specificity by homology
Recommended dilution  
 HIF2A抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information HIF2A抗体
Immunogen: HIF2A fusion protein ag15199 Full Name: Endothelial PAS domain protein 1
Caculated Molecular
Weight:		 96 kDa Observed Molecular 
Weight:		  
GenbankNo BC051338 GeneID: 2034
Symbol EPAS1 Synonyms BHLHe73, ECYT4, EPAS 1, EPAS1, HIF 1 alpha like factor, HIF 2 alpha, HIF2 alpha, HIF2A, HLF, Member of PAS protein 2, MOP2, PASD2
Background

Endothelial PAS domain-containing protein 1 (EPAS1),also known as Hypoxia-inducible factor 2-alpha (HIF2-alpha,HIF2A),is a transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.EPAS1 is expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells.The molecular weight is about 96kd. HIF2A抗体

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