Anti-TM2D1抗体
产品名称： Anti-TM2D1抗体
英文名称： TM2D1
产品编号： YB--19942R
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
上海钰博生物科技有限公司
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- 所在区域 : 上海
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Anti-TM2D1抗体
| 产品编号 | YB-19942R |
| 英文名称 | TM2D1 |
| 中文名称 | β淀粉样蛋白结合蛋白抗体 |
| 别 名 | BBP; Beta amyloid binding protein; hBBP; TM2 domain containing 1; TM2 domain containing protein 1; TM2D1. |
| 规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 细胞凋亡 Alzheimer's |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 19kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TM2D1:38-100/207 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq, Dec 2008] Function: May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42. Subunit: Interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed. Post-translational modifications: N-glycosylated. Similarity: Belongs to the TM2 family. SWISS: Q9BX74 Gene ID: 83941 Database links: Entrez Gene: 83941 Human Entrez Gene: 94043 Mouse Entrez Gene: 362545 Rat Omim: 610080 Human SwissProt: Q9BX74 Human SwissProt: Q99MB3 Mouse Unigene: 656790 Human Unigene: 331719 Mouse Unigene: 198278 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |