FITC标记的糖原生成素相互作用蛋白抗体
产品名称： FITC标记的糖原生成素相互作用蛋白抗体
英文名称： Anti-TRIM7/FITC
产品编号： HZ-9164R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-TRIM7/FITC Conjugated antibody
FITC标记的糖原生成素相互作用蛋白抗体
| 产品编号 | bs-9164R-FITC |
| 英文名称 | Anti-TRIM7/FITC |
| 中文名称 | FITC标记的糖原生成素相互作用蛋白抗体 |
| 别 名 | Glycogenin-interacting protein; GNIP; RING finger protein 90; RNF90; TRIM7; TRIM7_HUMAN; Tripartite Motif Containing 7; Tripartite motif protein TRIM 7; Tripartite motif-containing protein 7. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 57kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRIM7/RNF90 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM7 (tripartite motif-containing 7), also known as RNF90 or GNIP, is a 511 amino acid protein that belongs to the TRIM family and contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Expressed in placenta and skeletal muscle and present at lower levels in brain, heart and pancreas, TRIM7 localizes to both the cytoplasm and the nucleus where it exists as dimers and is thought to participate in the initiation of glycogen synthesis. Multiple isoforms of TRIM7 exist due to alternative splicing events. Subunit: Forms homodimers and heterodimers. Interacts with GYG and DES. Tissue Specificity: Skeletal muscle and placenta, at lower levels in heart, brain and pancreas. Isoform 1 is widely expressed with high level in testis, kidney and heart. Similarity: Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 B30.2/SPRY domain. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 81786 Human Omim: 609315 Human SwissProt: Q9C029 Human Unigene: 487412 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
蛋白质的三部分基序（TIM）的特征在于保守的修剪域，其包括卷曲线圈区域、B-盒型锌指、一个环指和三个锌结合域。Trim7（包含7的三部分基序），也称为RNF90或GNIP，是属于修剪家族的511个氨基酸蛋白质，包含一个环型锌指、一个B盒型锌指和一个SRY域。在胎盘和骨骼肌中表达，存在于脑、心脏和胰腺的较低水平，TIM7定位于细胞质和细胞核，其中存在二聚体，并被认为参与糖原合成的起始。TIM7的多个异构体由于选择性剪接事件而存在。