TTC37 抗体Applications
In-house applications |
ELISA, WB, IHC, IF, IP Application not tested? Please see our Guarantee. |
Published applications |
WB |
Publications |
1 citations –view here |
Species specificity |
Human, Mouse; other species not tested. |
Published Species |
Human |
Images
Prev12Next
- HeLa cells were subjected to SDS PAGE followed by western blot with 24594-1-AP( TTC37 Antibody) at dilution of 1:300
- IP Result of anti-TTC37 (IP:24594-1-AP, 4ug; Detection:24594-1-AP 1:300) with mouse testis tissue lysate 4000ug.
- Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 24594-1-AP( TTC37 Antibody) at dilution of 1:50 (under 40x lens)
- Immunohistochemistry of paraffin-embedded human kidney tissue slide using 24594-1-AP( TTC37 Antibody) at dilution of 1:50 (under 40x lens)
- Immunofluorescent analysis of HepG2 cells using 24594-1-AP( TTC37 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
|
Positive WB detected in |
HeLa cells, HEK-293 cells, MCF-7 cells, mouse testis tissue |
Positive IP detected in |
Mouse testis tissue |
Positive IHC detected in |
Human kidney tissue, human tonsillitis tissue |
Positive IF detected in |
HepG2 cells |
Recommended dilution |
WB : 1:200-1:1000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100 |
TTC37 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source |
Rabbit |
Purification method |
Antigen affinity purification |
Isotype |
IgG |
Storage |
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information TTC37 抗体
Immunogen |
TTC37 fusion protein ag18442 |
Full name |
Tetratricopeptide repeat domain 37 |
Calculated molecular
weight |
1564aa,175 kDa |
Observed molecular
weight |
140-150 kDa |
GenBank accession
number |
BC056893 |
Gene ID (NCBI) |
9652 |
Gene symbol |
TTC37 |
Synonyms |
KIAA0372, TPR repeat protein 37, TTC37 |
Background
TTC37 (tetratricopeptide repeat protein 37), also named as Thespin, encodes 1,564 amino acid protein that contains twenty tetratricopeptide (TPR) repeats. TPR repeat-containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Although not expressed in liver, TTC37 is a widely expressed protein with highest levels of expression in vascular tissues, lymph node, pituitary, lung and intestine. TTC37 is a component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). Defects in TTC37 are associated with Trico-Hepato-Enteric (THE) syndrome. TTC37 抗体
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