Anti-BRD2抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-BRD2抗体

Anti-BRD2抗体

商家询价

产品名称: Anti-BRD2抗体

英文名称: BRD2

产品编号: YB--12888R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-BRD2抗体

产品编号 YB-12888R
英文名称 BRD2
中文名称 BRD2蛋白抗体
别    名 BRD 2; Brd2; BRD2_HUMAN; Bromodomain containing 2; BROMODOMAIN CONTAINING PROTEIN2; Bromodomain-containing protein 2; D6S113E; DKFZp686N0336; female sterile homeotic related gene 1; FLJ31942; FSH; FSRG1; KIAA9001; NAT; O27.1.1; Really interesting new gene 3 protein; Ring3; RING3 PROTEIN; RNF3.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 信号转导  激酶和磷酸酶  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BRD2:301-400/801 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Function:
May play a role in spermatogenesis or folliculogenesis.

Subunit:
Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'.

Subcellular Location:
Nucleus.

Similarity:
Contains 2 bromo domains.
Contains 1 ET domain.

SWISS:
P25440

Gene ID:
6046

Database links:

Entrez Gene: 6046 Human

Entrez Gene: 14312 Mouse

Entrez Gene: 294276 Rat

Omim: 601540 Human

SwissProt: P25440 Human

SwissProt: Q7JJ13 Mouse

SwissProt: Q6MGA9 Rat

Unigene: 75243 Human

Unigene: 3444 Mouse

Unigene: 98146 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.