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CHD4 染色质解旋酶DNA结合蛋白Mi2β抗体
货号:ym-CV13893R
规 格:0.1ml/0.2m
浓 度:1mg/1ml.
抗体来源:Rabbit / mouse
克隆类型:兔来源为polyclonal,鼠来源为monoclonal
产品类型:一抗 单抗
性 状:冻干粉或液体
亚 型:IgG
纯化方法:affinity purified by Protein A
储 存 液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
应用领域(仅适用于科研实验): Western blotting、Immunohistocry、ELISA、IF、IHC-P、IHC-F等,具体适用的实验请来电咨询,本公司有同一产品适用于不同实验的抗体。
保存条件: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
备注: 本产品仅供研究实验使用,不得用于治疗或诊断.
CHD4 染色质解旋酶DNA结合蛋白Mi2β抗体抗体原理
(1)特异性结合抗原:抗体本身不能直接溶解或杀伤带有特异抗原的靶细胞,通常需要补体或吞噬细胞等共同发挥效应以清除病原微生物或导致病理损伤。然而,抗体可通过与病毒或毒素的特异性结合,直接发挥中和病毒的作用。
(2)激活补体:IgM、IgG1、IgG2和IgG3可通过经典途径激活补体,凝聚的IgA、IgG4和IgE可通过替代途径激活补体。
(3)结合细胞:不同类别的免疫球蛋白,可结合不同种的细胞,参与免疫应答。
(4)可通过胎盘及粘膜:免疫球蛋白G(IgG)能通过胎盘进入胎儿血流中,使胎儿形成自然被动免疫。免疫球蛋白A(IgA)可通过消化道及呼吸道粘膜,是粘膜局部抗感染免疫的主要因素。
(5)具有抗原性:抗体分子是一种蛋白质,也具有刺激机体产生免疫应答的性能。不同的免疫球蛋白分子,各具有不同的抗原性。
(6)抗体对理化因子的抵抗力与一般球蛋白相同:不耐热,60~70℃即被破坏。各种酶及能使蛋白质凝固变性的物质,均能破坏抗体的作用。抗体可被中性盐类沉淀。在生产上常可用硫酸铵或硫酸钠从免疫血清中沉淀出含有抗体的球蛋白,再经透析法将其纯化。
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